Born: Sarasota, Florida, USA
Gugino was born in Sarasota, Florida, to Carl Gugino, an orthodontist of Italian descent, and a mother of English-Irish descent described as "Bohemian". She is known for her roles as Ingrid Cortez in the Spy Kids trilogy, Sally Jupiter in Watchmen (2009), Dr. Vera Gorski in Sucker Punch (2011), and as the lead characters of the television series Karen Sisco and Threshold. Her feature film work includes starring roles in Son in Law (1993), Sin City (2005), Night at the Museum (2006), Mr. Popper's Penguins (2011) and San Andreas (2015), as well as Kelor in the DC Extended Universe. Gugino has had lead roles in the TV series Political Animals (2012), Wayward Pines (2015), and Roadies (2016).
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